CP-84364

CAT: 0804-HY-121866Size: 1 EachDry Ice: NoHazardous: No

CAT#:0804-HY-121866Size:1 Each

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Description

Hippeastrine hydrobromide is an active alkaloid that exhibits a good dose-dependent inhibitory effect on topoisomerase I (Top I) with an IC50 of 7.25 μg/mL. Hippeastrine hydrobromide exhibits antiproliferative and anticancer activities.

CAS Number

[114457-62-4]

UNSPSC

12352005

Target

Topoisomerase

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/cp-84364.html

Smiles

O=C(O)[C@H](CC1=CC=CC=C1)NC(N2CCOCC2)=O

Molecular Formula

C14H18N2O4

Molecular Weight

278.30

References & Citations

[1]Quantitation of 4-cyclohexyl-2-hydroxy-3- (3-methylsulfanyl-2-{2- [ (morpholine-4-carbonyl) amino]-3- phenylpropionylamino}propionylamino) butyric acid isopropyl ester (CP-80,794), a renin inhibitor, and its hydrolytic cleavage metabolite 2-[ (morpholine-4-carbonyl) amino]-3-phenylpropionic acid (CP-84,364) in dog and human plasma by high-performance liquid chromatography

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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