Recombinant Human MIP-5/CCL15 protein

Recombinant Human MIP-5/CCL15 protein

• Background: Human CCL15 is belonging to the CC chemokine family and shares 35 % amino acid homology with human HCC1 (CCL14). CCL15 is most abundant in heart, skeletal muscle and adrenal gland, and low expressed in liver, small intestine, colon, and in certain leukocytes and macrophages of the lung. It is chemotactic for neutrophils, monocytes, and lymphocytes and elicits its effects by binding to cell surface chemokine receptors like CCR1 and CCR3. CCL15 has several cleaved chains. All of them are more potent chemoattractants than CCL15.
• CAS Number: 9000-83-3
• Reconstitution: Lyophilized from a .2 μm filtered solution of 2mM TrisHCl, 15mM NaCl, 1mM DTT, pH 8..
• Molecular Weight: Approximately 1.2 kDa, a single non-glycosylated polypeptide chain containing 92 amino acids.