MIP-5 (CCL15)

• Description :

  MIP-5 is a CC chemokine that is expressed in the heart, skeletal muscle and adrenal gland. MIP-5 primarily signals through he CCR1 receptor, but also has been found to bind to CCR3. MIP-5 is chemotactic towards T cells and monocytes. Recombinant human MIP-5 is a 10.1 kDa protein containing 92 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

• Synonyms :

  CCL15; LKN1; NCC3; SY15; HCC-2; LKN-1; MIP-5; NCC-3; SCYL3; MIP-1D; MRP-2B; SCYA15; HMRP-2B

• NCBI Gene ID :

  6359

• UniProt :

  Q16663

• Accession Number :

  NP_116741.1

• Accession Number mRNA :

  NM_032965

• Chromosomal Location :

  17q11.2

• Reactivity :

  Human

• Cross Reactivity :

  Mouse, Human

• Sequence :

  QFTNDAETEL MMSKLPLENP VVLNSFHFAA DCCTSYISQS IPCSLMKSYF ETSSECSKPG VIFLTKKGRQ VCAKPSGPGV QDCMKKLKPY SI

• Endotoxin :

  < 0.1 ng/µg of protein (< 1EU/µg)

• Purity :

  > 98% by SDS-PAGE & HPLC analyses

• Bioactivity :

  Determined by its ability to chemoattract human T lymphocytes using a concentration range of 1.0-10.0 ng/ml.

• Length :

  92

• Form :

  Lyophilized

• Molecular Weight :

  10.1 kDa

• Host or Source :

  E. coli