Recombinant Mouse MIP-2/CXCL2 protein

Recombinant Mouse MIP-2/CXCL2 protein

• Background: Mouse CXCL2, also named MIP-2, is belonging to the CXC chemokine family. It is encoded by the gene CXCL2. CXCL2 shares 90 % amino acid sequence with CXCL1/GROα. It is member of the intercrine alpha (chemokine C-X-C) subfamily of chemokines. This chemokine is secreted from a Mouse macrophage cell line. The functional receptor for CXCL2 has been identified as CXCR2. CXCL2 is chemotactic for polymorphonuclear leukocytes and hematopoietic stem cells. Similar to other GRO proteins, CXCL2 is potent neutrophil attractants and activators. In addition, it is also active toward basophils. The amino acid sequence of Mouse CXCL2 is 60 % identical to human CXCL2.
• CAS Number: 9000-83-3
• Reconstitution: Supplied as a .2 μm filtered solution of 2mM Tris, 15mM NaCl, pH 7.5.
• Molecular Weight: Approximately 7.8 kDa, a single, non-glycosylated polypeptide chain containing 73 amino acids.