SM-433

• Description :

  SM-433, a Smac mimetic, function as inhibitor of inhibitor of apoptosis proteins (IAPs) . SM-433 exhibits strong binding affinity XIAP BIR3 protein with an IC50[1].

• UNSPSC :

  12352005

• Target :

  Apoptosis; IAP

• Type :

  Reference compound

• Related Pathways :

  Apoptosis

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/sm-433.html

• Purity :

  99.01

• Solubility :

  DMSO : 160 mg/mL (ultrasonic)

• Smiles :

  O=C([C@@H]1CC[C@@](CCN(C(CC(C)C)=O)C[C@@H]2NC([C@@H](NC)C)=O)([H])N1C2=O)NCC3=CC=CC=C3C4=CC=CC=C4

• Molecular Formula :

  C32H43N5O4

• Molecular Weight :

  561.71

• References & Citations :

  [1]Shaomeng Wang, et al. Diazo bicyclic smac mimetics and the uses thereof. WO2008128171A2.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, sealed storage, away from moisture and light)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1071992-81-8]