HU 433

• Description:

  HU 433 is a synthetic cannabinoid CB2 receptor agonist and is the enantiomer of HU 308 (HY-161510) . HU 433 exerts its anti-inflammatory and neuroprotective effects by binding to CB2 receptors. HU 433 can be used in the study of neuroinflammation and retinal diseases[1].

• UNSPSC:

  12352005

• Target:

  Cannabinoid Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology; Neurological Disease; Others

• Assay Protocol:

  https://www.medchemexpress.com/hu-433.html

• Smiles:

  COC1=C(C(OC)=CC(C(C)(CCCCCC)C)=C1)[C@@H]2C=C([C@@H]3C[C@H]2C3(C)C)CO

• Molecular Formula:

  C27H42O3

• Molecular Weight:

  414.62

• References & Citations:

  [1]Young A P, et al. Enantiomeric Agonists of the Type 2 Cannabinoid Receptor Reduce Retinal Damage during Proliferative Vitreoretinopathy and Inhibit Hyperactive Microglia In Vitro[J]. ACS Pharmacology & Translational Science, 2024.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [1220887-84-2]