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Phrixotoxin 2

CAT: 0804-HY-P2786ASize: 1 EachDry Ice: NoHazardous: No
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Description
Phrixotoxin 2 is a highly selective KV4.2 and KV4.3-channels blocker[1].
CAS Number
741738-57-8
UNSPSC
12352209
Target
Potassium Channel
Type
Peptides
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/phrixotoxin-2.html
Solubility
10 mM in DMSO
Smiles
O=C([C@@H](N)CC1=CC=C(O)C=C1)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H]2CSSC[C@H](NC3=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N)=O)CCSC)=O)CC(N)=O)=O)[C@H](CC)C)=O)[C@H](CC)C)=O)CCCNC(N)=N)=O)CCCCN)=O)=O)CCCCN)=O)CCCNC(N)=N)=O)CCC(O)=O)=O)CCC(O)=O)=O)CC(O)=O)=O)CSSC[C@H](NC4=O)C(N[C@H](C(N[C@H](C(N[C@H]3CC5=CNC6=CC=CC=C56)=O)CC(C)C)=O)CCCNC(N)=N)=O)=O)[C@@H](C)O)=O)CC7=CNC8=CC=CC=C78)=O)CCSC)=O)CC9=CNC%10=CC=CC=C9%10)=O)CCCCN)=O)CCC(N)=O)=O)CSSC[C@H](NC2=O)C(N[C@H](C(NCC(N[C@H](C(N[C@H]4C(C)C)=O)CC(C)C)=O)=O)CCC(O)=O)=O
Molecular Formula
C169H259N49O43S8
Molecular Weight
3921.69
References & Citations
[1]M. Gostimirovic, et al. Involvement of phrixotoxin-2 sensitive KV4 family of potassium channels in the relaxation mediated by resveratrol in human saphenous vein from diabetic patients. Abstracts / Atherosclerosis 331 (2021) e56ee293.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

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