Phrixotoxin 2

• Description:

  Phrixotoxin 2 is a highly selective KV4.2 and KV4.3-channels blocker[1].

• UNSPSC:

  12352209

• Target:

  Potassium Channel

• Type:

  Peptides

• Related Pathways:

  Membrane Transporter/Ion Channel

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/phrixotoxin-2.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C ([C@@H] (N) CC1=CC=C (O) C=C1) N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H]2CSSC[C@H] (NC3=O) C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N) =O) CCSC) =O) CC (N) =O) =O) [C@H] (CC) C) =O) [C@H] (CC) C) =O) CCCNC (N) =N) =O) CCCCN) =O) =O) CCCCN) =O) CCCNC (N) =N) =O) CCC (O) =O) =O) CCC (O) =O) =O) CC (O) =O) =O) CSSC[C@H] (NC4=O) C (N[C@H] (C (N[C@H] (C (N[C@H]3CC5=CNC6=CC=CC=C56) =O) CC (C) C) =O) CCCNC (N) =N) =O) =O) [C@@H] (C) O) =O) CC7=CNC8=CC=CC=C78) =O) CCSC) =O) CC9=CNC%10=CC=CC=C9%10) =O) CCCCN) =O) CCC (N) =O) =O) CSSC[C@H] (NC2=O) C (N[C@H] (C (NCC (N[C@H] (C (N[C@H]4C (C) C) =O) CC (C) C) =O) =O) CCC (O) =O) =O

• Molecular Formula:

  C169H259N49O43S8

• Molecular Weight:

  3921.69

• References & Citations:

  [1]M. Gostimirovic, et al. Involvement of phrixotoxin-2 sensitive KV4 family of potassium channels in the relaxation mediated by resveratrol in human saphenous vein from diabetic patients. Abstracts / Atherosclerosis 331 (2021) e56ee293.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Peptides

• Clinical Information:

  No Development Reported

• CAS Number:

  741738-57-8