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(KO Validated) IGF1R Polyclonal Antibody

CAT: 0866-RD86735A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD86735A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Description
This is a (KO Validated) IGF1R Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
IGF1R, CD221, IGFIR, IGFR, JTK13
Gene ID
3480
Swiss Prot
P08069
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human IGF1R
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.01% thiomersal,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
21kDa/54kDa/57kDa
Observed Molecular Weight
57KDa
Host or Source
Rabbit
Isotype
IgG

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