Products for Research Use Only

(KO Validated) CBX3 Polyclonal Antibody

CAT: 0866-RD82616A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD82616A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.
Description
This is a (KO Validated) CBX3 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
CBX3, HECH, HP1-GAMMA, HP1Hs-gamma
Gene ID
11335
Swiss Prot
Q13185
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human CBX3 (NP_009207.2) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
20 kDa
Observed Molecular Weight
23 kDa
Host or Source
Rabbit
Isotype
IgG