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(KO Validated) PARP1 Polyclonal Antibody

CAT: 0866-RD90291A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD90291A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a chromatin-associated enzyme, poly (ADP-ribosyl) transferase, which modifies various nuclear proteins by poly (ADP-ribosyl) ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.
Description
This is a (KO Validated) PARP1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
PARP1, ADPRT, ADPRT 1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1, poly (ADP-ribose) polymerase 1
Gene ID
142
Swiss Prot
P09874
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human PARP1
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000, IHC 1:50-1:100, IF 1:50-1:200
Buffer
PBS with 0.01% thiomersal,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
97kDa
Observed Molecular Weight
43KDa
Host or Source
Rabbit
Isotype
IgG

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