(KO Validated) PSAP Polyclonal Antibody

CAT: 0866-RD90340A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD90340A-01Size:60 μL
Selected
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
This gene encodes a highly conserved preproprotein that is proteolytically processed to generate four main cleavage products including saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
Description
This is a (KO Validated) PSAP Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
PSAP, GLBA, SAP1, prosaposin
Gene ID
5660
Swiss Prot
P07602
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human PSAP
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Buffer
PBS with 0.05% proclin300,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
62kDa/70kDa/97kDa/134kDa/136kDa/137kDa
Observed Molecular Weight
185KDa
Host or Source
Rabbit
Isotype
IgG

Popular Products