RegisterLogin

PSAP Polyclonal Antibody

CAT: 0498-bs-2241RSize: 100 µLDry Ice: NoHazardous: No
CAT#:0498-bs-2241RSize:100 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
PSAP is a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A, B, C, and D, which are similar to each other and are sphingolipid hydrolase activator proteins. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in PSAP gene have been associated with Gaucher disease, Tay-Sachs disease, and metachromatic leukodystrophy.
Synonyms
A1 activator; Cerebroside sulfate activator; Co-beta-glucosidase; Component C; CSAct; Dispersin; GLBA; Glucosylceramidase activator; Proactivator polypeptide; Proactivator polypeptide precursor; Prosaposin sphingolipid activator protein 1; prosaposin variant Gaucher disease and variant metachromatic leukodystrophy; Protein A; Protein C; PSAP; SAP-1; SAP-2; SAP_HUMAN; SAP1; Saposin A; Saposin B; Saposin B Val; Saposin C; Saposin-D; Saposins; Sphingolipid activator protein 1; Sphingolipid activator protein 2; Sulfated glycoprotein 1; Sulfatide/GM1 activator.
Gene ID
5660
Swiss Prot
P07602
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Human
Immunogen
421-524/524
Target
PSAP
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human PSAP
Applications
WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
5660

Related Products

CatalogName
bsm-62251R-01PSAP Recombinant Antibody
bsm-62251R-TRPSAP Recombinant Antibody
bsm-62251R-PEPSAP Recombinant Antibody, PE Conjugated
bsm-62251R-PerCPPSAP Recombinant Antibody, PerCP Conjugated
bsm-62251R-Cy3PSAP Recombinant Antibody, Cy3 Conjugated
bsm-62251R-HRPPSAP Recombinant Antibody, HRP Conjugated
bsm-62251R-FITCPSAP Recombinant Antibody, FITC Conjugated
bsm-62251R-BiotinPSAP Recombinant Antibody, Biotin Conjugated
bsm-62251R-APCPSAP Recombinant Antibody, APC Conjugated
bsm-62251R-Cy5PSAP Recombinant Antibody, Cy5 Conjugated

Alternative Products

CatalogName
E55A01633PSAP Polyclonal Antibody
TA354500PSAP Rabbit Polyclonal Antibody
TMAB-11844-01Anti-PSAP Polyclonal Antibody
NBP1-83363Rabbit Polyclonal PSAP Antibody
GTR04072114-01Polyclonal Antibody to Prosaposin (PSAP)

Popular Products