Anti-2b protein [Cucumber mosaic virus]

• Background:

  2b protein [Cucumber mosaic virus]is one of the first identified suppressors that could inhibit post-transcriptional gene silencing (PTGS), but with little or no effect on miRNA functions. CMV 2b protein also interferes with miRNA pathways, eliciting developmental anomalies.

• Host:

  Rabbit

• Reactivity:

  2b protein [Cucumber mosaic virus]

• Not reactive in:

  No confirmed exceptions from predicted reactivity are currently known

• Immunogen:

  Recombinant 2b protein [Cucumber mosaic virus] Protein accession number:NP_619631.

• Clonality:

  Polyclonal

• Applications:

  Western Blot (WB)

• Dilution:

  1 : 5000 (WB)

• Purity:

  Serum

• Format:

  Lyophilized

• Reconstitution:

  For reconstitution add 50 µl of sterile water

• Molecular Weight:

  12.7 | 18 kDa

• References & Citations:

  Wuet al. (2020). WUSCHEL triggers innate antiviral immunity in plant stem cells. Science. 2020 Oct 9;370(6513):227-231. doi: 10.1126/science.abb7360. PMID: 33033220.Nemeset al. (2019). Symptom recovery is affected by Cucumber mosaic virus coat protein phosphorylation. Virology Volume 536, October 2019, Pages 68-77.Zhanget al (2006). Cucumber mosaic virus-encoded 2b suppressor inhibits Arabidopsis Argonaute1 cleavage activity to counter plant defense. Genes & development 20: 3255-3268.

• Storage Conditions:

  Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.

• CAS Number:

  9007-83-4