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(KO Validated) LITAF Polyclonal Antibody

CAT: 0866-RD83324A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD83324A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppressor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget's disease (EMPD) . Multiple alternatively spliced transcript variants have been found for this gene.
Description
This is a (KO Validated) LITAF Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
LITAF, PIG7, SIMPLE, TP53I7
Gene ID
9516
Swiss Prot
Q99732
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein of human LITAF (NP_004853.2) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000 IHC 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
15 kDa/17 kDa/23 kDa
Observed Molecular Weight
20 kDa
Host or Source
Rabbit
Isotype
IgG

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