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(KO Validated) APEX1 Polyclonal Antibody

CAT: 0866-RD82710A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD82710A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein.
Description
This is a (KO Validated) APEX1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
APEX1, APE, APE1, APEN, APEX, APX, HAP1, REF1
Gene ID
328
Swiss Prot
P27695
Reactivity
Human
Immunogen
Recombinant fusion protein of human APEX1 (NP_542380.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000 IF 1:50-1:100
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
35 kDa
Observed Molecular Weight
39 kDa
Host or Source
Rabbit
Isotype
IgG

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