Complement Component C5a Human Recombinant Protein

• Description:

  C5a Human Recombinant produced in E. coli is a single, non-glycosylated, polypeptide chain containing 74 amino acids and having a molecular mass of 8.3kDa. The Human C5a is purified by proprietary chromatographic techniques.

• Synonyms:

  Complement Component 5; C3 and PZP-Like Alpha-2-Macroglobulin Domain-Containing Protein 4; C5a Anaphylatoxin; Prepro-C5; CPAMD4; Anaphylatoxin C5a Analog; ECLZB; C5A; C5D; C5b; C5

• Gene Name:

  C5

• UniProt:

  P01031

• Reactivity:

  Human

• Source:

  Escherichia coli

• Sequence:

  [object Object]

• Purification:

  Greater than 98.0% as determined by (a) Analysis by RP-HPLC and (b) Analysis by SDS-PAGE.

• Bioactivity:

  The biological activity determined by its ability to chemoattract human monocytes using a concentration range of 1.0-10.0 ng/ml.

• Form:

  Sterile Filtered White lyophilized (freeze-dried) powder.

• Reconstitution:

  2

• Function:

  Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled.

• Shipping Conditions:

  Available

• Storage Conditions:

  Lyophilized Human C5a although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Human C5a should be stored at 4°C between 2-7 days and for future use below -18°C. Please prevent freeze-thaw cycles.

• Other Gene Names:

  Complement C5

• Subcellular Location:

  Secreted.