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Complement Component C5a Human Recombinant Protein

CAT: 0519-PROTP01031-01Size: 5 µgDry Ice: NoHazardous: No
CAT#:0519-PROTP01031-01Size:5 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
C5a Human Recombinant produced in E. coli is a single, non-glycosylated, polypeptide chain containing 74 amino acids and having a molecular mass of 8.3kDa. The Human C5a is purified by proprietary chromatographic techniques.
Synonyms
Complement Component 5; C3 and PZP-Like Alpha-2-Macroglobulin Domain-Containing Protein 4; C5a Anaphylatoxin; Prepro-C5; CPAMD4; Anaphylatoxin C5a Analog; ECLZB; C5A; C5D; C5b; C5
Gene Name
C5
UniProt
P01031
Reactivity
Human
Source
Escherichia coli
Sequence
[object Object]
Purification
Greater than 98.0% as determined by (a) Analysis by RP-HPLC and (b) Analysis by SDS-PAGE.
Bioactivity
The biological activity determined by its ability to chemoattract human monocytes using a concentration range of 1.0-10.0 ng/ml.
Form
Sterile Filtered White lyophilized (freeze-dried) powder.
Reconstitution
2
Function
Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled.
Shipping Conditions
Available
Storage Conditions
Lyophilized Human C5a although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Human C5a should be stored at 4°C between 2-7 days and for future use below -18°C. Please prevent freeze-thaw cycles.
Other Gene Names
Complement C5
Subcellular Location
Secreted.

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