Products for Research Use Only
RegisterLogin

KN-92 (phosphate)

CAT: 0804-HY-15517A-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-15517A-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
KN-92 phosphate is an inactive derivative of KN-93, without CaM kinase inhibitory activity. KN-92 phosphate is intended to be used as a control compound in studies designed to elucidate the antagonist activities of KN-93. KN-93 is a cell-permeable, reversible and competitive CaMKII inhibitor[1][2].
CAS Number
1135280-28-2
UNSPSC
12352005
Hazard Statement
H315, H317, H319, H335, H360
Target
Autophagy; CaMK
Type
Reference compound
Related Pathways
Autophagy; Neuronal Signaling
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/KN-92-phosphate.html
Purity
99.68
Solubility
DMSO : 50 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL (ultrasonic)
Smiles
O=S(C1=CC=C(OC)C=C1)(NC2=CC=CC=C2CN(C/C=C/C3=CC=C(Cl)C=C3)C)=O.O=P(O)(O)O
Molecular Formula
C24H28ClN2O7PS
Molecular Weight
554.98
Precautions
H315, H317, H319, H335, H360
References & Citations
[1]Smyth JT, et al. Inhibition of the inositol trisphosphate receptor of mouse eggs and A7r5 cells by KN-93 via a mechanism unrelated to Ca2+/calmodulin-dependent protein kinase II antagonism. J Biol Chem. 2002;277 (38) :35061-35070.|[2]An P, et al. KN-93, a specific inhibitor of CaMKII inhibits human hepatic stellate cell proliferation in vitro. World J Gastroenterol. 2007;13 (9) :1445-1448.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Citation 01
J Endocrinol. 2018 Mar;236 (3) :151-165. |Nat Metab. 2020 Sep;2 (9) :918-933.|Sci Rep. 2023 Dec 7;13 (1) :21712.|Cell Calcium. 2021 Dec:100:102483.|Commun Biol. 2025 Mar 12;8 (1) :417.|J Mol Cell Cardiol. 2022 Mar:164:110-125.

Related Products

CatalogName
HY-15517-01KN-92
HY-15517B-01KN-92 (hydrochloride)
HY-15465B-01KN-93 (phosphate)
HY-110140-01(E) -KN-93 (phosphate)
HY-162346KN-17
HY-15465-01KN-93
HY-13290-01KN-62
HY-15465A-01KN-93 (hydrochloride)
HY-176221α-Glucosidase-IN-92
HY-175857HDAC-IN-92

Alternative Products

CatalogName
A3531-200KN-92 phosphate
A15139-100KN-92 phosphate 100mg
A15139-2KN-92 phosphate 2mg
A15139-25KN-92 phosphate 25mg
A15139-5KN-92 phosphate 5mg
A15139-200KN-92 phosphate 200mg
A15139-50KN-92 phosphate 50mg
A15139-10KN-92 phosphate 10mg
A15139-1KN-92 phosphate 1mg

Popular Products