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ML191

CAT: 0804-HY-111083-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-111083-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ML-191 is an antagonist of GPR55. It inhibits GPR55 signaling induced by lysophosphatidylinositol (EC50=1.076 µM in U2OS cells overexpressing GPR55) . ML-191 inhibits LPI-induced phosphorylation of ERK1/2 (IC50=328 nM) and receptor-dependent translocation of PKCβII when used at a concentration of 30 µM[1].
CAS Number
[931695-79-3]
Product Name Alternative
CID23612552
UNSPSC
12352005
Target
GPR55
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ml191.html
Concentration
10mM
Purity
99.81
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1OC(C2=CC=CC=C2)=NN1C3CCN(C(C4(C5=CC=C(C)C=C5)CC4)=O)CC3
Molecular Formula
C24H25N3O3
Molecular Weight
403.47
References & Citations
[1]Heynen-Genel S, et al. Screening for Selective Ligands for GPR55 - Antagonists. 2010 Oct 30
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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555950ML191
A22088-1ML191 1mg
A22088-10ML191 10mg
A22088-50ML191 50mg
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A22088-25ML191 25mg
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