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ML121

CAT: 0804-HY-128049Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-128049Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ML121 is a selective and potent VIM-2 inhibitor with an IC50 of 54 nM and a Ki of 148 nM. ML121 shows inactive in IMP-1 and TEM-1 beta-lactamase assays. ML121 can potentiate the antibiotic activity of Imipenem in VIM-2 transformed E.coli[1].
CAS Number
1212185-26-6
UNSPSC
12352005
Target
Beta-lactamase
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
O=C1SC(C(C2=CC=CN=C2)C3C(C4CCC3C4)S5)=C5N1
Molecular Formula
C16H16N2OS2
Molecular Weight
316.44
References & Citations
[1]Minond D, Set al. HTS Assay for Discovery of Novel Metallo-Beta-lactamase (MBL) Inhibitors. 2009 Nov 13. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD) : National Center for Biotechnology Information (US) .
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Metallo-β-lactamase (MBL)

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