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ML192

CAT: 0804-HY-122246-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-122246-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ML192 is a selective ligand antagonist of GPR55. ML192 inhibits the β-arrestin trafficking, ERK1/2 phosphorylation and PKCβII translocation[1].
CAS Number
[460331-61-7]
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
Arrestin; ERK; GPR55; PKC
Type
Reference compound
Related Pathways
Epigenetics; GPCR/G Protein; MAPK/ERK Pathway; Neuronal Signaling; Stem Cell/Wnt; TGF-beta/Smad
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/ml192.html
Concentration
10mM
Purity
99.70
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(N1CCN(CC1)C2=C3C(CCCC4)=C4SC3=NC(C)=N2)C5=CC=CO5
Molecular Formula
C20H22N4O2S
Molecular Weight
382.48
Precautions
H302, H315, H319
References & Citations
[1]Kotsikorou E, et al. Identification of the GPR55 antagonist binding site using a novel set of high-potency GPR55 selective ligands. Biochemistry. 2013 Dec 31;52 (52) :9456-69.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ERK1; ERK2; PKCβ

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