Recombinant Mouse TPBG/5T4 (C-6His)
CAT:
763-PKSM041401-01
Size:
50 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Recombinant Mouse TPBG/5T4 (C-6His)
- Background: Trophoblast glycoprotein, also known as TPBG and 5T4, it belongs to the LRR family of proteins. The C-terminus of LRR N-terminal cap (LRRNT) and LRR 1 are essential for the inhibition of the Wnt signaling pathway. TPBG may function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. It expressed by all types of trophoblasts as early as 9 weeks of development. In adult tissues, the expression is limited to a few epithelial cell types but is found on a variety of carcinoma.
- Abbreviation: TPBG;5T4
- Synonyms: 5T4 Protein, 5T4AG Protein, Human, M6P1 Protein, WAIF1 Protein
- CAS Number: 9000-83-3
- UniProt: Q9Z0L0
- Accession Number: Q9Z0L0
- Host: HEK293 Cells
- Origin Species: Mouse
- Tag: C-His
- Sequence: Ser32-Ser361
- Purity: > 95 % as determined by reducing SDS-PAGE.
- Bioactivity: Not validated for activity
- Reconstitution: Not Applicable
- Molecular Weight: 50-70 kDa
- Shipping Conditions: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
- Storage Conditions: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.