Recombinant Mouse GM-CSF/CSF2 Protein

CAT: 0763-PKSM041031-01Size: 20 µgDry Ice: NoHazardous: No

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CAT#:0763-PKSM041031-01Size:20 µg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) was initially characterized as a growth factorthat can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by anumber of different cell types (including activated T cells, B cells, macrophages, mast cells, endothelial cellsand fibroblasts) in response to cytokine of immune and inflammatory stimuli. Besides granulocyte-macrophageprogenitors, GM-CSF is also a growth factor for erythroid, megakaryocyte and eosinophil progenitors. Onmature hematopoietic, monocytes/ macrophages and eosinophils. GM-CSF has a functional role on nonhematopoitic cells. It can induce human endothelial cells to migrate and proliferate. Additionally, GM-CSF canalso stimulate the proliferation of a number of tumor cell lines, including osteogenic sarcoma, carcinoma andadenocarcinoma cell lines.

Abbreviation

GM-CSF; CSF2

Synonyms

Colony-stimulating factor; Csf2; Csfgm; GM-CSF; Granulocyte-macrophage colony-stimulating factor

UniProt

P01587

Accession Number

P01587

Expression System

E.coli

Tag

N-His

Sequence

Ala18-Lys141

Applications

Cell culture

Endotoxin

< 0.1 EU per μg of the protein as determined by the LAL method.

Purity

> 98 % as determined by reducing SDS-PAGE.

Bioactivity

502 x 107 IU/mg.7

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

15.1 kDa

Observed Molecular Weight

17 kDa

Species

Mouse

UniProtKB · P01587

Granulocyte-macrophage colony-stimulating factor

CSF2_MOUSE · Mus musculus

View on UniProt ↗

Primary accession: P01587
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: Csf2
Protein existence: 1: Evidence at protein level
Organism: Mus musculus (Mouse)
Taxonomy ID: 10090
Alternative names: GM-CSF
EC number: —
Processing: Precursor
Secondary accessions: —

Protein keywords

Molecular function

CytokineGrowth factor

Technical term

Direct protein sequencingReference proteome

PTM

Disulfide bondGlycoprotein

Cellular component

Secreted

Domain

Signal

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Alternative Products

Catalog	Name
32-8572-50	Recombinant Mouse GM-CSF/CSF2
Z200077	Recombinant Mouse GM-CSF (CSF2)
PR00201	Recombinant Mouse CSF2/GM-CSF Protein
TMPY-04114-01	GM-CSF/CSF2 Protein, Mouse, Recombinant
MBS2553508-01	Recombinant Mouse GM-CSF/CSF2 Protein
PPT-16472	Mouse CSF2/GM-CSF Recombinant Protein
MOP2170-01	Recombinant Mouse GM-CSF/Csf2 Protein, No Tag
ARP5532-01	Recombinant Human GM-CSF/CSF2 Protein
PR00367	Recombinant Human CSF2/GM-CSF Protein
TMPY-03631-01	GM-CSF/CSF2 Protein, Mouse, Recombinant (hFc)