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Recombinant Human SENP2 Protein

CAT: 0763-PKSH033026-01Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0763-PKSH033026-01Size:10 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
SENP2 is an enzyme that belongs to the peptidase C48 family. SENP2 is a protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. SUMO1 is a small ubiquitin-like protein that can be covalently conjugated to other proteins. It has been implicated as a down-regulator of CTNNB1 levels and may therefore be a modulator of the Wnt pathway.
Abbreviation
SENP2
Synonyms
Axam2; KIAA1331; SENP2. ; SMT3-specific isopeptidase 2; Sentrin-specific protease 2; Sentrin/SUMO-specific protease SENP2
UniProt
Q9HC62
Accession Number
Q9HC62
Expression System
E.coli
Tag
None
Sequence
Asp363-Leu589
Field of Research
Cell biology; epigenetics and nuclear signal
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
26.8 kDa
Observed Molecular Weight
29 kDa
Formulation
Supplied as a 0.2 μm filtered solution of 50mM HEPES,5% Glycerol, pH 7.4.
Species
Human

UniProtKB · Q9HC62

Sentrin-specific protease 2

SENP2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9HC62
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SENP2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.4.22.-
Processing
—
Secondary accessions
B4DQ42, Q8IW97, Q96SR2, Q9P2L5
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

CytoplasmMembraneNuclear pore complexNucleus

Molecular function

HydrolaseProteaseThiol protease

Biological process

mRNA transportProtein transportTranslocationTransportUbl conjugation pathwayWnt signaling pathway

PTM

PhosphoproteinUbl conjugation
Product Datasheet
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