FIT-039
CAT:
804-HY-18944-06
Size:
50 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
FIT-039
- CAS Number: 1113044-49-7
- UNSPSC Description: FIT-039 is a selective, ATP-competitive and orally active CDK9 inhibitor with an IC50 of 5.8 μM for CKD9/cyclin T1. FIT-039 does not inhibit other CDKs and other kinases. FIT-039 inhibits replication of HSV-1 (IC50 of 0.69 μM), HSV-2, human adenovirus, and human CMV. FIT-039 is a promising antiviral agent for inhibiting drug-resistant HSVs and other DNA viruses.
- Target Antigen: CDK; CMV; DNA/RNA Synthesis; HSV
- Type: Reference compound
- Related Pathways: Anti-infection;Cell Cycle/DNA Damage
- Applications: COVID-19-anti-virus
- Field of Research: Infection
- Assay Protocol: https://www.medchemexpress.com/fit-039.html
- Purity: 99.56
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: FC1=CC(NC(C2=CC=NC=C2)=S)=C(N3CCCCC3)C=C1
- Molecular Weight: 315.41
- References & Citations: [1]Makoto Yamamoto, et al. CDK9 Inhibitor FIT-039 Prevents Replication of Multiple DNA Viruses. J Clin Invest. 2014 Aug;124(8):3479-88.
- Shipping Conditions: Blue Ice
- Storage Conditions: -20°C, 3 years (Powder)
- Clinical Information: No Development Reported