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SORD Polyclonal Antibody

CAT: 0763-E-AB-53170-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-53170-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Sorbitol dehydrogenase (SORD; EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1; MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]) . The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD (+) cofactor.
Abbreviation
SORD
UniProt
Q00796
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Fusion protein of human SORD
Target
DHSO; L iditol 2 dehydrogenase; L-iditol 2-dehydrogenase; OTTHUMP00000161939; SDH; Sorbitol dehydrogenase 1; Sorbitol dehydrogenase; SORD 1; SORD; SORD1
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Metabolism; Signal Transduction
Purification
Antigen affinity purification
Concentration
0.78 mg/mL
Dilution
IHC 1:50-1:100
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

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