RITA1 Polyclonal Antibody

• Background:

  Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. May play a role in neurogenesis.

• Abbreviation:

  RITA1

• UniProt:

  Q96K30

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Fusion protein of human RITA1

• Target:

  C12orf52 ; Chromosome 12 open reading frame 52 ; RBPJ interacting and tubulin associated 1; RBPJ interacting and tubulin associated protein 1; RBPJ-interacting and tubulin-associated protein; RITA; RITA

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  IHC

• Field of Research:

  Developmental biology; Neuroscience; Signal transduction; Stem cells

• Purification:

  Antigen affinity purification

• Concentration:

  1.02 mg/mL

• Dilution:

  IHC 1:50-1:200

• Buffer:

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Isotype:

  IgG