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AP1S3 Polyclonal Antibody

CAT: 0763-E-AB-19098-02Size: 60 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-19098-02Size:60 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the adaptor-related protein complex 1, sigma subunit genes. The encoded protein is a component of adaptor protein complex 1 (AP-1), one of the AP complexes involved in claathrin-mediated vesicular transport from the Golgi or endosomes. Disruption of the pathway for display of HIV-1 antigens, which prevents recognition of the virus by cytotoxic T cells, has been shown to involve the AP-1 complex (PMID: 15569716) . Alternative splicing results in multiple transcript variants.
Abbreviation
AP1S3
UniProt
Q96PC3
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Fusion protein of human AP1S3
Target
Adapter-related protein complex 1 subunit sigma-1C; Adaptor protein complex AP 1 sigma 1C subunit; Adaptor protein complex AP-1 subunit sigma-1C; Adaptor related protein complex 1 sigma 3 subunit; AP-1 complex subunit sigma-3; Ap1s3; AP1S3; Clathrin assembly protein complex 1 sigma-1C small chain; Golgi adaptor HA1/AP1 adaptin sigma-1C subunit; Sigma 1C subunit of AP-1 clathrin; Sigma-adaptin 1C; Sigma1C-adaptin
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Purification
Antigen affinity purification
Concentration
1.26 mg/mL
Dilution
IHC 1:100-1:300
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

UniProtKB · Q96PC3

AP-1 complex subunit sigma-3

AP1S3_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q96PC3
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
AP1S3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B4DQZ1, Q8WTY1, Q96DD1
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Coated pitCytoplasmic vesicleGolgi apparatusMembrane

Disease

Disease variant

Biological process

Protein transportTransport

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