BPGM Polyclonal Antibody

• Background:

  2,3-diphosphoglycerate (2,3-DPG) is a small molecule found at high concentrations in red blood cells where it binds to and decreases the oxygen affinity of hemoglobin. This gene encodes a multifunctional enzyme that catalyzes 2,3-DPG synthesis via its synthetase activity, and 2,3-DPG degradation via its phosphatase activity. The enzyme also has phosphoglycerate phosphomutase activity. Deficiency of this enzyme increases the affinity of cells for oxygen. Mutations in this gene result in hemolytic anemia. Multiple alternatively spliced variants, encoding the same protein, have been identified.

• Abbreviation:

  BPGM

• UniProt:

  P07738

• Host:

  Rabbit

• Reactivity:

  Human; Mouse

• Immunogen:

  Full length fusion protein

• Target:

  2;2;3-bisphosphoglycerate mutase;2;3-bisphosphoglycerate mutase; erythrocyte;2;3-bisphosphoglycerate synthase;2;3-diphosphoglycerate mutase;3-bisphosphoglycerate mutase;3-bisphosphoglycerate synthase;3-diphosphoglycerate mutase; Ab2 098; AI323730; AL022789; Bisphosphoglycerate mutase; BPG dependent PGAM; BPG-dependent PGAM; Bpgm; C86192; DPGM; Erythrocyte 2;3 bisphosphoglycerate mutase; erythrocyte; PMGE

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  WB; IHC

• Field of Research:

  Cancer; Cardiovascular; Metabolism; Signal transduction

• Purification:

  Antigen affinity purification

• Concentration:

  1.1 mg/mL

• Dilution:

  WB 1:1000-1:5000; IHC 1:50-1:300

• Buffer:

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  30 kDa

• Observed Molecular Weight:

  Refer to figures

• Isotype:

  IgG