PPOX Polyclonal Antibody

• Background :

  This gene encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. Mutations in this gene cause variegate porphyria, an autosomal dominant disorder of heme metabolism resulting from a deficiency in protoporphyrinogen oxidase, an enzyme located on the inner mitochondrial membrane. Alternatively spliced transcript variants encoding the same protein have been identified.

• Abbreviation :

  PPOX

• UniProt :

  P50336

• Host :

  Rabbit

• Reactivity :

  Human; Mouse

• Immunogen :

  Synthetic peptide of human PPOX

• Target :

  MGC8485; PPO; PPOX; PPOX; Protoporphyrinogen oxidase; V290M; Variegate porphyria; VP

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Applications :

  WB; IHC

• Field of Research :

  Cancer; Metabolism; Tags and Cell markers

• Purification :

  Affinity purification

• Concentration :

  0.5 mg/mL

• Dilution :

  WB 1:1000-1:5000; IHC 1:50-1:200

• Buffer :

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Shipping Conditions :

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions :

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  51kDa

• Isotype :

  IgG