BBC3 Polyclonal Antibody

• Background :

  This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants.

• Abbreviation :

  BBC3

• UniProt :

  Q9BXH1

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  Synthetic peptide of human BBC3

• Target :

  BBC 3; Bbc3; BBC3; BCL 2 binding component 3; Bcl-2-binding component 3; BCL2 binding component 3; JFY 1; JFY-1; JFY1; p53 up regulated modulator of apoptosis; p53 up-regulated modulator of apoptosis; p53 Upregulated Modulator of Apoptosis; PUMA alpha; PUMA/JFY1

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Applications :

  WB

• Field of Research :

  Cancer; Cell Biology; Metabolism; Signal Transduction

• Purification :

  Affinity purification

• Concentration :

  0.9 mg/mL

• Dilution :

  WB 1:200-1:1000

• Buffer :

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Shipping Conditions :

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions :

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  21kDa

• Isotype :

  IgG