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FUCA1 Polyclonal Antibody

CAT: 0763-E-AB-15050-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-15050-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a lysosomal enzyme involved in the degradation of fucose-containing glycoproteins and glycolipids. Mutations in this gene are associated with fucosidosis (FUCA1D), which is an autosomal recessive lysosomal storage disease. A pseudogene of this locus is present on chr 2.
Abbreviation
FUCA1
UniProt
P04066
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Recombinant protein of human FUCA1
Target
Alpha L fucosidase I; Alpha L fucoside fucohydrolase; Alpha-L-fucosidase 1; Alpha-L-fucosidase I; Alpha-L-fucoside fucohydrolase 1; FUCA; FUCA1; FUCO; fucosidase; alpha-L; tissue; fucosidase; alpha-L- 1; tissue; Tissue alpha L fucosidase; Tissue alpha-L-fucosidase
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Metabolism; Signal Transduction
Purification
Affinity purification
Concentration
0.7 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
54kDa
Isotype
IgG

UniProtKB · P04066

Tissue alpha-L-fucosidase

FUCO_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P04066
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
FUCA1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.2.1.51
Processing
Precursor
Secondary accessions
B2RBG3, Q14334, Q14335, Q3LID0, Q8NAC2
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Disease

Disease variant

PTM

GlycoproteinPhosphoprotein

Molecular function

GlycosidaseHydrolase

Biological process

Lipid metabolism

Cellular component

Lysosome

Domain

Signal

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