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AMBRA1 Polyclonal Antibody

CAT: 0763-E-AB-10787-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-10787-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Human AMBRA1, which encodes a deduced 1,269-amino acid protein. Ambra1 was expressed throughout development in mice, with strong staining in the neuroepithelium. Regulates autophagy and development of the nervous system. Involved in autophagy in controlling protein turnover during neuronal development, and in regulating normal cell survival and proliferation. Interacts with BECN1. Probably forms a complex with BECN1 and PIK3C3.
Abbreviation
AMBRA1
UniProt
Q9C0C7
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Recombinant protein of human AMBRA1
Target
Activating molecule in beclin 1 regulated autophagy; Activating molecule in BECN1 regulated autophagy protein 1; Activating molecule in BECN1-regulated autophagy protein 1; Ambra1; AMRA1; Autophagy and beclin 1 regulator 1; DCAF3; FLJ20294; Hypothetical protein FLJ20294; Hypothetical protein LOC55626; KIAA1736; MGC33725; WDR94
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Cardiovascular; Metabolism; Neuroscience; Signal Transduction
Purification
Affinity purification
Concentration
0.3 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

UniProtKB · Q9C0C7

Activating molecule in BECN1-regulated autophagy protein 1

AMRA1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9C0C7
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
AMBRA1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A6XN33, D3DQP8, G3V193, Q86XD6, Q9H8Z0, Q9NXE7
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

AutophagyCell cycleDifferentiationNeurogenesisTranscriptionTranscription regulationUbl conjugation pathway

Cellular component

Cell junctionCytoplasmCytoplasmic vesicleCytoskeletonEndoplasmic reticulumMitochondrionNucleus

Molecular function

Developmental protein

PTM

Isopeptide bondMethylationPhosphoproteinUbl conjugation

Domain

RepeatWD repeat

Disease

Tumor suppressor

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