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TA-01

CAT: 0804-HY-100114-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-100114-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TA-01 is a potent CK1 and p38 MAPK inhibitor, with IC50s of 6.4 nM, 6.8 nM, 6.7 nM for CK1ε, CK1δ and p38 MAPK, respectively. TA-01 acts as a cardiogenic inhibitor.
CAS Number
[1784751-18-3]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Autophagy; Casein Kinase; p38 MAPK
Type
Reference compound
Related Pathways
Autophagy; Cell Cycle/DNA Damage; MAPK/ERK Pathway; Stem Cell/Wnt
Applications
COVID-19-anti-virus
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/TA-01.html
Purity
99.86
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
FC(C=C1)=CC=C1C2=C(C3=CC=NC=C3)NC(C4=C(F)C=CC=C4F)=N2
Molecular Formula
C20H12F3N3
Molecular Weight
351.32
Precautions
H302, H315, H319, H335
References & Citations
[1]Laco F, et al. Cardiomyocyte differentiation of pluripotent stem cells with SB203580 analogues correlates with Wnt pathway CK1 inhibition independent of p38 MAPK signaling. J Mol Cell Cardiol. 2015 Mar;80:56-70.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CK1; p38 MAPK

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Alternative Products

CatalogName
bs-6705C-01TA-01
B4923-5.1TA 01
A16236-25TA-01 25mg
A16236-5TA-01 5mg
A16236-100TA-01 100mg
A16236-50TA-01 50mg
A16236-200TA-01 200mg
A16236-2TA-01 2mg
A16236-10TA-01 10mg
A16236-10mM-DTA-01 10mM * 1mL in DMSO

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