SNIPER(TACC3)-2

• UNSPSC Description:

  SNIPER(TACC3)-2 targets the TACC3 protein for degradation via the ubiquitin-proteasome pathway based on IAP ligand. SNIPER(TACC3)-2 induces cancer cell death[1].

• Target Antigen:

  SNIPERs

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/sniper-tacc3-2.html

• Purity:

  99.81

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(NCCOCCOCCOCCNC([C@H](CC(C)C)NC([C@H]([C@@H](CC1=CC=CC=C1)N)O)=O)=O)C2=CC=C(C3=NC(CNC4=NC=CC(NCC(C)C)=N4)=CS3)C=C2

• Molecular Weight:

  848.07

• References & Citations:

  [1]Ohoka N, et al. Cancer cell death induced by novel small molecules degrading the TACC3 protein via the ubiquitin-proteasome pathway. Cell Death Dis. 2014 Nov 6;5:e1513.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Clinical Information:

  No Development Reported