Anti-Integrator complex subunit 2 INTS2 Antibody

• Description:

  Boster Bio Anti-Integrator complex subunit 2 INTS2 Antibody catalog # A15434. Tested in IHC applications. This antibody reacts with Human.

• Synonyms:

  Integrator complex subunit 2; Int2; INTS2; KIAA1287;

• Gene Name:

  INTS2

• UniProt:

  Q9H0H0

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Synthetic peptide, corresponding to amino acids 50-100 of Human INTS2.

• Clonality:

  Polyclonal

• Applications:

  IHC

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Dilution:

  IHC: 1:50-1:200

• Form:

  Liquid

• Function:

  Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable) . Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex (PubMed:23904267) .

• Molecular Weight:

  134323 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Other Gene Names:

  Integrator complex subunit 2

• Subcellular Location:

  Nucleus membrane

• Protein Name:

  Integrator complex subunit 2