Anti-Condensin complex subunit 2 NCAPH Antibody

• Description:

  Boster Bio Anti-Condensin complex subunit 2 NCAPH Antibody (Catalog# A30627) . Tested in WB, ELISA applications. This antibody reacts with Human, Rat, Mouse.

• Synonyms:

  NCAPH; BRRN; BRRN1; CAPH; KIAA0074; Condensin complex subunit 2; Barren homolog protein 1; Chromosome-associated protein H; hCAP-H; Non-SMC condensin I complex subunit H; XCAP-H homolog

• Gene Name:

  NCAPH

• UniProt:

  Q15003

• Host:

  Rabbit

• Reactivity:

  Human, Rat, Mouse

• Immunogen:

  A peptide derived from human NCAPH. Immunogen sequence location: 441-490

• Clonality:

  Polyclonal

• Tissue Specificity:

  Widely expressed at low level. Expressed in proliferating cells.

• Applications:

  WB, ELISA

• Field of Research:

  Cell Biology, Cell Cycle, Cell Division, Chromosome Structure, Epigenetics and Nuclear Signaling

• Purification:

  The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

• Concentration:

  0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

• Form:

  Liquid

• Function:

  Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.

• Molecular Weight:

  82563 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Fragment:

  Rabbit IgG

• Other Gene Names:

  Condensin complex subunit 2

• Subcellular Location:

  Nucleus. Cytoplasm. Chromosome. In interphase cells, the majority of the condensin complex is found in the cytoplasm, while a minority of the complex is associated with chromatin. A subpopulation of the complex however remains associated with chromosome foci in interphase cells. During mitosis, most of the condensin complex is associated with the chromatin. At the onset of prophase, the regulatory subunits of the complex are phosphorylated by CDK1, leading to condensin's association with chromosome arms and to chromosome condensation. Dissociation from chromosomes is observed in late telophase.