Anti-Integrator complex subunit 6 INTS6 Antibody

• Description:

  Boster Bio Anti-Integrator complex subunit 6 INTS6 Antibody catalog # A07753. Tested in WB applications. This antibody reacts with Human, Mouse.

• Synonyms:

  Integrator complex subunit 6; Int6; DBI-1; Protein DDX26; Protein deleted in cancer 1; DICE1; INTS6; DBI1, DDX26, DDX26A;

• Gene Name:

  INTS6

• UniProt:

  Q9UL03

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant fusion protein of human INTS6 (NP_036273.1) .

• Clonality:

  Polyclonal

• Tissue Specificity:

  Widely expressed. Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.

• Applications:

  WB

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Dilution:

  WB: 1:500-1:2000

• Form:

  Liquid

• Function:

  Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable) . Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex (PubMed:23904267) . May have a tumor suppressor role; an ectopic expression suppressing tumor cell growth (PubMed:15254679, PubMed:16239144) .

• Molecular Weight:

  100390 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Other Gene Names:

  Integrator complex subunit 6

• Subcellular Location:

  Nucleus

• Protein Name:

  Integrator complex subunit 6