Anti-AP-2 complex subunit mu AP2M1 Antibody

• Background:

  The heterotetrameric coat assembly protein complex, also known as the adaptor-related protein complex 2 (AP-2), belongs to the adaptor complexes medium subunits family. The mu 1 subunit of the AP-2 complex (AP2M1) is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. AP2M1 has also been shown to associate with the HIV-1 protein Nef, suggesting that Nef may use AP-2 complex to enhance the rate of endocytosis of both CD4 and class I MHC. AP2M1 may also play an important role in regulating the intracellular trafficking and function of cytotoxic T-lymphocyte associated (CTLA)-4 protein. At least two isoforms of AP2M1 are known to exist.

• Description:

  Boster Bio Anti-AP-2 complex subunit mu AP2M1 Antibody (Catalog # A06179-1). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

• Synonyms:

  mu2, AP50, CLAPM1, KIAA0109, AP-2 complex subunit mu, AP-2 mu chain

• Gene Name:

  AP2M1

• UniProt:

  Q96CW1

• Host:

  Chicken

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  AP2M1 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human AP2M1. The immunogen is located within amino acids 360 - 410 of AP2M1.

• Clonality:

  Polyclonal

• Applications:

  ELISA, WB, IHC-P, IF

• Purification:

  AP2M1 Antibody is affinity chromatography purified via peptide column.

• Concentration:

  1 mg/mL

• Form:

  Liquid

• Molecular Weight:

  49655 MW

• Components:

  AP2M1 Antibody is supplied in PBS containing 0.02% sodium azide.

• Storage Conditions:

  AP2M1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Fragment:

  IgY

• CAS Number:

  9007-83-4