BCN-PEG4-HyNic
CAT:
804-HY-136061
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
BCN-PEG4-HyNic
- CAS Number: 1507370-54-8
- UNSPSC Description: BCN-PEG4-HyNic is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. BCN-PEG4-HyNic is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
- Target Antigen: ADC Linker
- Type: ADC Related
- Related Pathways: Antibody-drug Conjugate/ADC Related
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/bcn-peg4-hynic.html
- Solubility: 10 mM in DMSO
- Smiles: O=C(NCCOCCOCCOCCNC(OC[C@@H]1[C@@]2(CCC#CCC[C@@]21[H])[H])=O)C3=CN=C(N/N=C(C)\C)C=C3
- Molecular Weight: 543.66
- References & Citations: [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported