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LY-3381916

CAT: 0804-HY-111540-01Size: 10 mM - 1 mLDry Ice: NoHazardous: No
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CAT#:0804-HY-111540-01Size:10 mM - 1 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LY-3381916 (IDO1-IN-5) is a potent, selective and brain penetrated inhibitor of IDO1 activity, binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1[1].
CAS Number
2166616-75-5
Product Name Alternative
IDO1-IN-5
UNSPSC
12352005
Target
Indoleamine 2,3-Dioxygenase (IDO)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ly-3381916.html
Purity
99.92
Solubility
DMSO : 300 mg/mL (ultrasonic)
Smiles
FC1=CC=C(C(N[C@H](C)C2=CC=C(N(C(C3CCOCC3)=O)CC4)C4=C2)=O)C=C1
Molecular Formula
C23H25FN2O3
Molecular Weight
396.45
References & Citations
[1]Frank C. Dorsey, et al. Abstract 5245: Identification and characterization of the IDO1 inhibitor LY3381916. Cancer Research. 2018, 78 (13) .
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 1
Isoform
IDO1

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Alternative Products

CatalogName
BA7831-5LY-3381916
A19483-100LY-3381916 100mg
A19483-25LY-3381916 25mg
A19483-5LY-3381916 5mg
A19483-50LY-3381916 50mg
A19483-10LY-3381916 10mg
A19483-2LY-3381916 2mg
A19483-1LY-3381916 1mg
A19483-10mM-DLY-3381916 10mM * 1mL in DMSO
228143CD5 (Ly-1, Ly-12, Ly-A, T1, Tp67)

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