BigLEN(rat)

• UNSPSC Description:

  BigLEN(rat) is a potent GPR171 agonist with an EC50 of 1.6 nM[1].

• Target Antigen:

  GPR171

• Type:

  Peptides

• Related Pathways:

  GPCR/G Protein

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/biglen-rat.html

• Purity:

  98.98

• Solubility:

  H2O : ≥ 50 mg/mL

• Smiles:

  O=C(N1[C@@H](CCC1)C(O)=O)[C@H]2N(CCC2)C([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC([C@H](C)NC([C@H]3N(CCC3)C([C@H](C)NC([C@H](CCC(N)=O)NC([C@H]4N(CCC4)C([C@H](CO)NC([C@H](CO)NC([C@H](CC(N)=O)NC([C@H](CCC(O)=O)NC([C@@H](N)CC(C)C)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

• Molecular Weight:

  1745.98

• References & Citations:

  [1]Gomes I, et al. GPR171 is a hypothalamic G protein-coupled receptor for BigLEN, a neuropeptide involved in feeding. Proc Natl Acad Sci U S A. 2013;110(40):16211-16216

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)

• Clinical Information:

  No Development Reported

• CAS Number:

  369377-66-2