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IL-17 modulator 4

CAT: 0804-HY-141692-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-141692-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IL-17 modulator 4 is a proagent of IL-17 modulator 1. IL-17 modulator 1 is an orally active, highly efficacious IL-17 modulator. IL-17 modulator 4 is promising for the research of IL-17A mediated diseases, including inflammation, autoimmune diseases, infectious diseases, cancer, and precancerous syndrome[1][2].
CAS Number
2446803-65-0
UNSPSC
12352005
Target
Interleukin Related
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/il-17-modulator-4.html
Concentration
10mM
Purity
99.00
Solubility
DMSO : 300 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=NN1C(C)C)N[C@H](C(NC2=CC=C(C3=C(C)NN=C3C)C=C2)=O)C(C4CC4)C5CC5
Molecular Formula
C27H34N6O2
Molecular Weight
474.60
References & Citations
[1]Kevin Neil Dack, et al. Amino-acid anilides as small molecule modulators of il-17. WO2020127685A1.|[2]Zhang B, et al. Small molecule modulators of IL-17A/IL-17RA: a patent review (2013-2021) . Expert Opin Ther Pat. 2022 Nov;32 (11) :1161-1173. |[3]Andrews MD, et al., Discovery of an Oral, Rule of 5 Compliant, Interleukin 17A Protein-Protein Interaction Modulator for the Potential Treatment of Psoriasis and Other Inflammatory Diseases. J Med Chem. 2022 Jul 14;65 (13) :8828-8842.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
IL-17

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