IL-17 modulator 5

• Description :

  IL-17 modulator 5 (compound 26) is a IL-17 inhibitor, with an IC50 of 1 nM[1].

• UNSPSC :

  12352005

• Target :

  Interleukin Related

• Type :

  Reference compound

• Related Pathways :

  Immunology/Inflammation

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/il-17-modulator-5.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(C1=NON=C1C)N[C@H](C2=NC3=CC=C([C@@H](C4=NN=C5C=CC(C#N)=CN54)CC(F)(F)F)C(F)=C3N2)C6CCC(F)(F)CC6

• Molecular Formula :

  C28H23F6N9O2

• Molecular Weight :

  631.53

• References & Citations :

  [1]Ram W Sabnis, et al. Novel Difluorocyclohexyl Derivatives as IL-17 Modulators for Treating Inflammatory and Autoimmune Diseases. ACS Med Chem Lett. 2021 Nov 18;12 (12) :1883-1884.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  IL-17

• CAS Number :

  [2724206-27-1]