IL-17 modulator 2

• Description :

  IL-17 modulator 2 (compound 159) is an orally active modulator of IL-17. IL-17 modulator 2 significantly reduces IL-6, IFN-γ, and edema. IL-17 modulator 2 can used in study arthritis[1].

• UNSPSC :

  12352005

• Target :

  Interleukin Related

• Type :

  Reference compound

• Related Pathways :

  Immunology/Inflammation

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/il-17-modulator-2.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C([C@H](CC1=CC=CC=C1Cl)NC(CC2=CC=CC=C2)=O)NC3=CC=C(C[C@@H](NC4=O)C(NCC(NCCCCCNC(CC5(CCCC5)C4)=O)=O)=O)C=C3

• Molecular Formula :

  C42H51ClN6O6

• Molecular Weight :

  771.34

• References & Citations :

  [1]Michael Taylor, et al. Macrocyclic compounds for modulating IL-17. US9284283B2. 2016-03-15.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1449208-36-9]