IL-17 modulator 6

• Description:

  IL-17 modulator 6 (compound 61) is a potent Interleukin 17 (IL-17) modulator (pIC50=9.1) . IL-17 modulator 6 has the ability to inhibit IL-17 and can be used for the research of inflammatory and autoimmune diseases[1].

• UNSPSC:

  12352005

• Target:

  Interleukin Related

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/il-17-modulator-6.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=NON=C1C2CC2)N[C@@H](C3CCC(F)(CC3)F)C4=NC5=C(F)C([C@H](CC(F)F)C(NCC(F)(F)C)=O)=CC=C5N4

• Molecular Formula:

  C27H29F7N6O3

• Molecular Weight:

  618.55

• References & Citations:

  [1]Sabnis RW. Novel Difluorocyclohexyl Derivatives as IL-17 Modulators for Treating Inflammatory and Autoimmune Diseases. ACS Med Chem Lett. 2021;12 (12) :1883-1884. Published 2021 Nov 18.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  IL-17

• CAS Number:

  [2725869-16-7]