Products for Research Use Only
RegisterLogin

IA9 (TFA)

CAT: 0804-HY-P10136A-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-P10136A-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
IA9 TFA (human TREM-2 182-190 TFA) is a potent, CNS-penetrant TREM-2 inhibitor. IA9 TFA can diminish the release of proinflammatory cytokines and suppress joint inflammation and damage in a Collagen -induced arthritis (CIA) mouse model. IA9 TFA can be used for neuroinflammation PET imaging. IA9 TFA can be used for Rheumatoid arthritis (RA) and neuroinflammation research[1][2].
Product Name Alternative
Human TREM-2 182-190 (TFA)
UNSPSC
12352209
Target
TREM receptor
Type
Peptides
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ia9-tfa.html
Purity
98.90
Solubility
DMSO : 6.25 mg/mL (ultrasonic)
Smiles
O=C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC(C)C)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCCCN)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC(C)C)C(N[C@@H](C)C(N[C@@H](C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H]([C@@H](C)CC)N.O=C(C(F)(F)F)O.[x]
Molecular Formula
C51H88N10O10.xC2HF3O2
Molecular Weight
1001.31 (free acid)
References & Citations
[1]Sigalov AB. Inhibition of TREM-2 Markedly Suppresses Joint Inflammation and Damage in Experimental Arthritis. Int J Mol Sci. 2022;23 (16) :8857. Published 2022 Aug 9.|[2]Zonghua Luo, et al. Development of a Ga-68 Labeled Peptide Tracer Targeting TREM2 for Neuroinflammation PET Imaging. Journal of Nuclear Medicine. Jun 2025, 66 (supplement 1) 251786.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
TREM-2

Related Products

CatalogName
HY-P10136-01IA9
HY-P5380ATNO211 (TFA)
HY-P4668A-01Valylleucine (TFA)
HY-P11296A-01LLVK (TFA)
HY-P10927A-01BRP (TFA)
HY-P10333A-01LIH383 (TFA)
HY-P3970D-01KQFK (TFA)
HY-P3460A-01TDSRCVIGLYHPPLQVY (TFA)
HY-P1723ASpexin (TFA)
HY-P10471A-01MPSD (TFA)

Alternative Products

CatalogName
A8967-1EZM0414 TFA
C8651-10Pentosidine TFA
A8958-100Box5 TFA
B5867-200SCH772984 TFA
B8792-5GsMTx4 TFA
330135Gardiquimod TFA
563453Cenupatide TFA
563651SSM3 TFA
465293Alytesin TFA
465313Difelikefalin TFA

Popular Products