CDK8-IN-4

CDK8-IN-4

• CAS Number: 1613638-82-6
• UNSPSC Description: CDK8-IN-4 is an inhibitor of CDK8 extracted from patent WO2014090692A1, compound example 16, with an IC50 of 0.2 nM.
• Target Antigen: CDK
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/_R_-2-__5-_1H-indazol-5-yl_pyridin-3-yl_amino_-2-phenylethanol.html
• Purity: 99.39
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: OC[C@@H](C1=CC=CC=C1)NC2=CC(C3=CC4=C(NN=C4)C=C3)=CN=C2
• Molecular Weight: 330.38
• References & Citations: [1]Cheng Z, et al. Novel bi-ring phenyl-pyridines/pyrazines for the treatment of cancer. WO2014090692A1
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, sealed storage, away from moisture and light)
• Clinical Information: No Development Reported