CDK8-IN-1

CDK8-IN-1

• CAS Number: 1629633-48-2
• UNSPSC Description: CDK8-IN-1 is a potent and selective CDK8 inhibitor with an IC50 of 3 nM.
• Target Antigen: CDK
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/CDK8-IN-1.html
• Purity: 99.77
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: NC(C1=C(C(F)(F)F)C(C2=CC=NC=C2)=CN1)=O
• Molecular Weight: 255.20
• References & Citations: [1]Han X, et al. Discovery of potent and selective CDK8 inhibitors through FBDD approach. Bioorg Med Chem Lett. 2017 Sep 15;27(18):4488-4492.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported