CDK8-IN-1
CAT:
804-HY-103492-05
Size:
10 mM / 1 mL
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
CDK8-IN-1
- CAS Number: 1629633-48-2
- UNSPSC Description: CDK8-IN-1 is a potent and selective CDK8 inhibitor with an IC50 of 3 nM.
- Target Antigen: CDK
- Type: Reference compound
- Related Pathways: Cell Cycle/DNA Damage
- Applications: Cancer-Kinase/protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/CDK8-IN-1.html
- Purity: 99.77
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: NC(C1=C(C(F)(F)F)C(C2=CC=NC=C2)=CN1)=O
- Molecular Weight: 255.20
- References & Citations: [1]Han X, et al. Discovery of potent and selective CDK8 inhibitors through FBDD approach. Bioorg Med Chem Lett. 2017 Sep 15;27(18):4488-4492.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: No Development Reported